We help founders build

a healthier & more sustainable future.

Wireframe Ventures

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We help founders who

deploy AI & automation to

empower us

.

Investing in technology for people & planet

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Our Purpose.

We invest capital, time & belief to accelerate your success.

Every startup journey is unique - there's no single playbook that works for everyone, especially in the early days. We try to meet you where you are and help you get where you dream of going. We listen with empathy, we tell you the truth and we'll dive in to contribute hands-on support whenever you need it. You should expect nothing less from any investor.
We invest in driven founders who can build pioneering companies that improve our world.
We partner closely with our founders from the beginning, and we're on call when they need us most.

Harsh brings a lifetime of wisdom coupled with uncanny insight, empathy, and authentic conviction to his investments. He is single-handedly the 'accelerator' you wished existed. He'll be the first person I call when I start my next company."

Viswa Colluru

Founder & CEO, Enveda Biosciences
"
Our Portfolio.

Our founders are on a mission to build a better future.

Product.
Product.
Purpose.
People.
Product.
Purpose.
People.
People.
People.
People.
People.
Product.
Purpose.
People.
Product.
Purpose.
Product.
Product.
Purpose.
Purpose.
People.
Product.
Purpose.
People.
Product.
Purpose.
Purpose.
Bioscience

Improving human health with new diagnostics & therapeutics built with CRISPR

Mammoth Biosciences

Seed
January 2018
Discovering & commercializing novel CRISPR systems that enable new possibilities for expanding biology
Retail

Powering a new circular economy for the world's best retail brands

Trove

Seed
May 2013
Driven by a belief that sustainability is the only way forward for retail, helping brands succeed & the world thrive
Energy

The new interface for home energy

SPAN.io

Seed
December 2018
Making home energy connected & intuitive with a smart electrical panel that makes it easier to adopt clean energy
Enterprise

Empowering organizations to solve their most challenging problems

Palantir

Series A
October 2005
Software empowering organizations with the insights they need to solve complex, mission-critical problems (NYSE: PLTR)
Agriculture

Solving food waste at the farm level

Full Harvest

Seed
October 2016
Optimizing the agricultural supply chain with a business marketplace for imperfect & surplus produce
Retail

A new class of material, sustainably crafted from nature

Mycoworks

Series A
May 2019
Bioengineering a sustainable, high-performance & animal-free alternative to leather using fine mycelium
Bioscience

Applying AI to engineer next-generation cancer therapies

Reverie Labs

Seed
March 2018
Solutions for the most difficult, multi-objective medicinal chemistry problems to fill pressing medical needs
Financial Services

Believing in the power of values-based investing

OpenInvest

Seed
May 2017
Making it simple, and profitable, to align your investments with your values (acq. by JPMorgan, NYSE: JPM)
Energy

Simplifying renewable energy procurement for any corporation

LevelTen Energy

Series A
September 2017
The industry's leading platform for corporate energy buyers to find the right renewable energy solutions
Our Team.

Meet our founders.

Harsh Patel

  • Co-Founder
  • Managing Director

Paul Straub

  • Co-Founder
  • Managing Director

Committed to your success.

We started Wireframe to serve founders solving some of the world's most important challenges. Over the years as investors & operators, we've built networks and domain expertise across themes we care deeply about. And we've been fortunate to work closely with founders from inception to success. As 1st check investors, we are completely aligned with you from the start.

Our Community.

Climb together.

We're building a community where founders can share hard-earned lessons with their peers and pay it forward to the next generation when they succeed.